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The areas are tested before injection using the Minor starch-iodine
test whereby the specific
areas of sweating are identified and only those areas are treated. A Betadyne
solution is painted on the skin and
cornstarch is applied over it. The areas that have perspiration turn the
cornstarch dark blue. The injections are made with the thinnest needle
available. The injections under the arm require no anesthesia and with
the syringes being changed frequently, cause minor stinging.
There are approximately
15-20 injections per side, usually using 50 Units of Botox per side. For
injections of the hands and feet, twice the amount of Botox needs to be
utilized due to the larger surface area that needs to be treated and the
less diffuse spread of the Botox. Since 40-50 injections need to be given
per side (100 Units per side), we use nerve blocks to the hands and feet
to prevent any discomfort. These are easily done and make a great difference
to the patient.
The length of time
that the Botox works depends on the site. For axillary sweating, the mean
time of relief is about 7 months with some patients getting up to a year
of being sweat free. The hands and feet are sweat free for a mean of 4
months with some patients being sweat free for up to a year. 
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